Guided Bone Regeneration

Prof. Darko Božić

He is an Associate prof at the Department of Periodontology, School of Dental Medicine, Zagreb, Croatia. He works in Croatia’s biggest University Clinical Hospital (6000 employees) at the clinic for periodontology as a specialist in periodontology. In addition to that, he also works every day in his private clinic. Currently, he holds the position of the President of the Croatian Society of Periodontology. He is currently a member of the EFP executive committee and is president-elect, and since 2016 he also served as the EFP webmaster and member of the Communications Committee.

The focus of his research is proteomic analysis of cementoblasts and periodontal tissues for which he and his team received two prestigious IADR awards, in 2015 IADR, Boston 2nd place Hatton/Unilever senior clinical research award, Proteomic Analyses of Gingival Tissues in Patients with Aggressive Periodontitis and in 2014 the IADR/PER , Dubrovnik, Croatia 1st place Robert Frank senior clinical research award for the same study.

The main focus in his clinical work is the reconstruction of soft and hard tissues in periodontitis-affected patients with a special research interest in the application of growth factors, namely BMPs and hyaluronic acid in regenerative procedures as well as soft tissue reconstruction utilizing various collagen matrices.

He lectures extensively on various topics related to soft and hard tissue reconstruction with more than 80 invited lectures so far, many at international periodontal congresses such as the Europerio meetings and the Perio Master Clinic 2020. He frequently gives advanced clinical master class courses with live surgical procedures.



  • Patient with a distal mandibular edentulous ridge requiring implant placement
  • Flap elevation revealed significant loss of ridge height and width.
  • Edentulous ridge with significant loss of height and width
  • A small amount of autogenous bone was harvested leaving small cortical perforations.
  • The autogenous bone was mixed with xenograft material saturated with xHyA.
  • Placement and adaptation of the graft mixture onto the recipient site.
  • The graft mixture was covered with a resorbable collagen membrane (SMARTBRANE) and fixed with pins.
  • After 6 months: Significant gain of bone width with almost no residual graft particles visible.
  • Implants of 4mm width were placed in the correct prosthetic positions.
  • After 6 months: Cone beam computed tomography (CBCT) showing a significant amount of newly formed bone.