Bone grafting

Bonefill, Porous & Mix,
Block

Excellent alternative to autogenous and allogenous bone

The mineralized inorganic bone matrix of the Bonefill has a porous macro and micro structure similar to the human cortical and spongy bones. In granulate form, Bonefill Dense, Porous & Mix act as osteoconductive mechanism promoting bone growth and regeneration. With time, the Bonefill is partially remodeled through the action of osteoclasts and osteoblasts, being a viable alternative to autologous bone in defects suitable for its use and indication.

Indications

SMARTGRAFT REGEDENT

Anorganic Bone Mineral

• Granules

SMARTGRAFT Granules is a porous bone mineral matrix consisting predominantly of calcium phosphate. It is produced by removal of the organic components from porcine cancellous bone. The product is available in granular form or in an applicator.

Properties/Actions

The anorganic bone matrix of SMARTGRAFT Granules has interconnecting macro- and microscopic porous structure that supports the formation and ingrowth of new bone at the implantation site. The use of SMARTGRAFT Granules may be considered when autogenous bone is not indicated, or insufficient in quantity to fulfill the needs of the proposed surgical procedure.

SMARTGRAFT Granules is indicated for:

• Augmentation or reconstructive treatment of the alveolar ridge.
• Filling of infrabony periodontal defects.
• Filling of defects after root resection, apicoectomy, and cystectomy.
• Filling of extraction sockets to enhance preservation of the alveolar ridge.
• Elevation of the maxillary sinus floor.
• Filling of periodontal defects in conjunction with products intended for Guided Tissue Regeneration (GTR) and Guided Bone Regeneration (GBR).
• Filling of peri-implant defects in conjunction with products intended for Guided Bone Regeneration (GBR).

SMARTGRAFT

• Syringe

The delivery applicator is a pre-loaded open barrel syringe with a perforated cap for ease of hydration and placement of SMARTGRAFT.

INSTRUCTIONS FOR USE

• Remove the sterile pre-loaded SMARTGRAFT Syringe from packaging and hydrate with osseous coagulum, patient’s blood or sterile normal saline, as follows:
  • with the perforated cap left on the syringe, immerse the tip of the syringe in the fluid;
  • pull up on the plunger to draw the fluid into the syringe;
  • push down on the plunger to expel excess fluid/air;
  • pull and push action should be repeated three times or until the material is fully hydrated.
• Once hydrated, remove the perforated cap and deliver the hydrated granules to the defect site.

REGENERATION

Native porcine graft provides a human-like structure for balanced remodelling.
The anorganic bone mineral matrix has interconnections that reduce the bulk density of the graft and allows for more void space for the growth of new bones.
As a porcine-derived bone, Smartgraft accelerates alveolar bone healing as compared to Deproteinized Bovine Bone Mineral (DBBM).
The proprietary purification process preserves carbonate apatite, which has been shown to increase the bone forming activities of osteogenic cells and to enhance bioresorption of bone graft by osteoclasts.
The biocompatibility is supported by the proprietary purification process of the graft.

synthetic graft
HYDROXYAPATYT

Description

Hydroxyapatite, Ca10(PO4)6(OH)2 is a hydrated calcium phosphate, major component (about 95%) of the mineral phase of human bones and teeth. Used by the body to make up the skeleton due to its capacity to act as a calcium and phosphorus reserve. Due to its chemical similarity with the chemical phase of bone tissues, it is one of the most biocompatible materials known, promoting bone growth in regions where it is found (osteoconductive), establishing chemical bonds between it and the bone tissue (bioactive), allowing the proliferation of fibroblasts, osteoblasts and other bone cells, which are not different from the bone surface indicating a high surface chemical similarity.

Indications

The hydroxyapatite-based biomaterials have been widely used in bone replacement. Hydroxyapatite is a bone graft material indicated with success in orthopedic, cranio-maxillofacial and dental surgeries. It is recommended for the repair of cranial base defects, spinal fusion and orthopedic applications, besides bone graft around dental implants and metal hip prostheses.

Properties

Origin: 100% synthetic.
Phase Purity ≥ 95%.
Porosity: 80% Overall porosity.
Interconnecting pore system ensures fast revascularization.
Resorption: Long-Term volume stability.
Biocompatible.
Radiopaque: Allows the monitorization of osteointegration.
Easy to handle.

synthetic graft
BETA TCP

Description

Pure phase Beta tricalcium phosphate (ß-TCP) (Ca3(PO4)2) is a resorbable synthetic particulate ceramic made from Calcium Hydroxide (Ca(OH)2), Phosphoric Acid (H3PO4), with the proportion of Ca3(PO4)2 being 91.67% according to the X-Ray Diffraction test. It is used as matrix for bone tissue neoformation because, in terms of composition, it is identical to the bone matrix and allows the restoration of this tissue through the osteoconduction process.

Mode of Action

The first healing stage promotes the migration of vessels through porosities, followed by the migration of bone forming cells that suffer differentiation through contact with the mineral portion of the bone.

Indications

Beta TCP is a biomaterial used in bone graft procedures, and it is a synthetic bioceramic, elective for regenerative techniques in Periodontics, Implant Dentistry, Orthopedics or medical and dental surgery procedures that require bone neoformation. It can be used in the reconstruction of traumatic or degenerative bone wall defects, sinus floor elevation, periodontal or alveolar bone filling and osteotomies, as well as the site preservation and preparation. In medical procedures, it is used in orthopedics and traumatology cases such as correction of musculoskeletal tumors, spinal chord and cervical spine injuries.

Properties

Origin: 100% synthetic.
Phase Purity ≥ 95%.
Porosity: Over 80%.
Gradually and completely resorbable.