Bone grafting

Bonefill, Porous & Mix,

Excellent alternative to autogenous and allogenous bone

The mineralized inorganic bone matrix of the Bonefill has a porous macro and micro structure similar to the human cortical and spongy bones. In granulate form, Bonefill Dense, Porous & Mix act as osteoconductive mechanism promoting bone growth and regeneration. With time, the Bonefill is partially remodeled through the action of osteoclasts and osteoblasts, being a viable alternative to autologous bone in defects suitable for its use and indication.


Bonefill is recommended for filling bone defects and for volumetric increase in the following situations:

  • increase/reconstructions of alveolar crests, filling of post-extraction cavities,
  • filling of cavities produced by post-surgery treatment interventions of cysts,
  • granulomas and other lytic, oral and maxillofacial and dental pathologies,
  • preparation of implant and filling sites of bone dehiscence,
  • besides bone grafts in maxillary sinuses and in the periodontal area it can be used in filling bone defects and to support the membrane during guided bone regeneration.


The surface helps the absorption of proteins in the Bonefill Porous particles, enabling the efficient adhesion of the osteoblasts. This biological interaction enables a reliable bone formation.


The rapid and complete hydration with blood or saline solution is an important feature of the handling, new bone formation and clinical success. Its strong capillary action allows the rapid and efficient penetration of particles with fluids in the material, nutrients and blood through its three-dimensional network of the trabecular bone, resulting in excellent handling, application and predictability in daily clinical use.

Courtesy by. Dr Danilo Maeda

6 months sinus floor augmentation

Courtesy by. Dr Fábio Mizutani

6 months sinus floor augmentation

Courtesy by. Dr Danilo Maeda

6 months split crest


  • Material rigin: Femoral heads of cattle.
  • Physicochemical treatment: Chemically treated – Receiving a sequence of baths [3 chemical process steps].
  • Appearance: Whitish up to beige.
  • Structure density:  Controlled Inorganic particles of bovine matrix with high macro and micro porosity having a large inner surface area.
  • Shelf life: 5 years
  • Ca/P 1,67
  • Macroporosity ~65-80%
  • Pore size ~100 – 600 μm
  • Integration time estimated 6 – 9 months
  • Surface area measured by BET ~77,5 m2/g
  • Calcium 27.52%-32.97% w./w.
  • Phosphorous 13.56%-16.28% w./w.

Sticky Bone Bonefill Porous


The prices do not include VAT

43 EUR16001 Bonefill [0,10- 0,60 mm] Small 0,50cc0,5 g
43 EUR 16024Bonefill [0,60- 1,50 mm] Medium 0,50cc0,5 g
43 EUR 16026 Bonefill [1,50- 2,50 mm] Large 1,00cc0,5 g
101 EUR 16043 Bonefill [0,10- 0,60 mm] Small 2,60cc2,5 g
101 EUR16042 Bonefill [0,60- 1,50 mm] Medium 2,60cc2,5 g


The prices do not include VAT

51 EUR16894 Bonefill Porous [0,10- 0,60 mm] Small 0,75cc0,5 g
51 EUR 16911Bonefill Porous [0,60- 1,50 mm] Medium 1,05cc0,5 g
51 EUR16928 Bonefill Porous [1,50- 2,50 mm] Large 1,45cc0,5 g
101 EUR 16891 Bonefill Porous [0,10- 0,60 mm] Small 1,50cc1,0 g
101 EUR16892 Bonefill Porous [0,60- 1,50 mm] Medium 2,10cc1,0 g
101 EUR16893 Bonefill Porous [1,50- 2,50 mm] Large 3,00cc1,0 g
158 EUR16914 Bonefill Porous [0,60- 1,50 mm] Medium 5,25cc2,5 g


The prices do not include VAT

56 EUR16955 Bonefill Mix [0,10- 1,50 mm] Small/Medium 0,88cc0,5 g
56 EUR 16964Bonefill Mix [0,60- 1,50 mm] Medium/Medium0,5 g
105 EUR 16965 Bonefill Mix [0,60- 1,50 mm] Medium/Medium1,0 g
169 EUR 16966 Bonefill Mix [0,60- 1,50 mm] Medium/Medium2,5 g


Anorganic Bone Mineral

  • Granules

SMARTGRAFT Granules is a porous bone mineral matrix consisting predominantly of calcium phosphate. It is produced by removal of the organic components from porcine cancellous bone. The product is available in granular form or in an applicator.


The anorganic bone matrix of SMARTGRAFT Granules has interconnecting macro- and microscopic porous structure that supports the formation and ingrowth of new bone at the implantation site. The use of SMARTGRAFT Granules may be considered when autogenous bone is not indicated, or insufficient in quantity to fulfill the needs of the proposed surgical procedure.


SMARTGRAFT Granules is indicated for:

  • Augmentation or reconstructive treatment of the alveolar ridge.
  • Filling of infrabony periodontal defects.
  • Filling of defects after root resection, apicoectomy, and cystectomy.
  • Filling of extraction sockets to enhance preservation of the alveolar ridge.
  • Elevation of the maxillary sinus floor.
  • Filling of periodontal defects in conjunction with products intended for Guided Tissue Regeneration (GTR) and Guided Bone Regeneration (GBR).
  • Filling of peri-implant defects in conjunction with products intended for Guided Bone Regeneration (GBR).



  • Syringe

The delivery applicator is a pre-loaded open barrel syringe with a perforated cap for ease of hydration and placement of SMARTGRAFT.


  • Remove the sterile pre-loaded SMARTGRAFT Syringe from packaging and hydrate with osseous coagulum, patient’s blood or sterile normal saline, as follows:
    • with the perforated cap left on the syringe, immerse the tip of the syringe in the fluid;
    • pull up on the plunger to draw the fluid into the syringe;
    • push down on the plunger to expel excess fluid/air;
    • pull and push action should be repeated three times or until the material is fully hydrated.
  • Once hydrated, remove the perforated cap and deliver the hydrated granules to the defect site.



Native porcine graft provides a human-like structure for balanced remodelling.
The anorganic bone mineral matrix has interconnections that reduce the bulk density of the graft and allows for more void space for the growth of new bones.
As a porcine-derived bone, Smartgraft accelerates alveolar bone healing as compared to Deproteinized Bovine Bone Mineral (DBBM).
The proprietary purification process preserves carbonate apatite, which has been shown to increase the bone forming activities of osteogenic cells and to enhance bioresorption of bone graft by osteoclasts.
The biocompatibility is supported by the proprietary purification process of the graft.


Facilitates vascularization and bone ingrowth.

Smartgraft’s high porosity and large pores enhance vascularization, bone ingrowth and osteointegration of the implant after surgery.
Smartgraft’s macropores range from 0.1mm to 1.0mm.
Native porous carbonate apatite possesses the natural pore structure for cell conduction.


The rough surface of human-like porcine particles facilitates the attachment of new cells.




  1. Sticky bone can be prepared with this out-of-the box gel and Smartgraft in 3 minutes.
  2. As hydrophilic agent, hyaluronic acid (HA) stabilizes blood clot and attracts growth factors to support and accelerate bone formation.
  3. HA supports angiogenesis.
  4. HA’s high molecular weight reduces swelling and discomfort while supporting scar-less healing.
  5. HA has natural bacteriostatic properties.
  6. HA’s special formulation remains present throughout the various phases of the healing process due to its slow degradation pattern (several weeks).


The prices do not include VAT

57 EUR0114.101SMARTGRAFT Granules0,25 - 1,00 mm (0,5 cc)
76 EUR0114.102SMARTGRAFT Granules0,25 - 1,00 mm (1,0 cc)
140 EUR0114.103SMARTGRAFT Granules0,25 - 1,00 mm (2,0 cc)
226 EUR0114.105SMARTGRAFT Granules0,25 - 1,00 mm (4,0 cc)
76 EUR0114.112SMARTGRAFT Granules1,00 - 2,00 mm (1,0 cc)
140 EUR0114.113SMARTGRAFT Granules1,00 - 2,00 mm (2,0 cc)
85 EUR0114.451SMARTGRAFT Syringe0,25 - 1,00 mm (0,5 cc)


The prices do not include VAT

105 EUR16495 Bonefill Block [5 x 10 x 10 mm]0,5 g
132 EUR16498Bonefill Block [5 x 20 x 20 mm]0,5 g
193 EUR16493 Bonefill Block [10 x 10 x 40 mm]1,0 g

synthetic graft


Hydroxyapatite, Ca10(PO4)6(OH)2 is a hydrated calcium phosphate, major component (about 95%) of the mineral phase of human bones and teeth. Used by the body to make up the skeleton due to its capacity to act as a calcium and phosphorus reserve. Due to its chemical similarity with the chemical phase of bone tissues, it is one of the most biocompatible materials known, promoting bone growth in regions where it is found (osteoconductive), establishing chemical bonds between it and the bone tissue (bioactive), allowing the proliferation of fibroblasts, osteoblasts and other bone cells, which are not different from the bone surface indicating a high surface chemical similarity.


The hydroxyapatite-based biomaterials have been widely used in bone replacement. Hydroxyapatite is a bone graft material indicated with success in orthopedic, cranio-maxillofacial and dental surgeries. It is recommended for the repair of cranial base defects, spinal fusion and orthopedic applications, besides bone graft around dental implants and metal hip prostheses.


Origin: 100% synthetic.
Phase Purity
≥ 95%.
80% Overall porosity.
Interconnecting pore system ensures fast revascularization.

Long-Term volume stability.

: Allows the monitorization of osteointegration.
Easy to handle.




The prices do not include VAT

37 EUR16032 od 0,90 do 1,00 mm0,5 g - 1,70 cc
37 EUR16033od 1,41 mm0,5 g - 1,50 cc
60 EUR16035 od 1,71 mm1,0 g - 2,60 cc

synthetic graft


Pure phase Beta tricalcium phosphate (ß-TCP) (Ca3(PO4)2) is a resorbable synthetic particulate ceramic made from Calcium Hydroxide (Ca(OH)2), Phosphoric Acid (H3PO4), with the proportion of Ca3(PO4)2 being 91.67% according to the X-Ray Diffraction test. It is used as matrix for bone tissue neoformation because, in terms of composition, it is identical to the bone matrix and allows the restoration of this tissue through the osteoconduction process.

Mode of Action

The first healing stage promotes the migration of vessels through porosities, followed by the migration of bone forming cells that suffer differentiation through contact with the mineral portion of the bone.


Beta TCP is a biomaterial used in bone graft procedures, and it is a synthetic bioceramic, elective for regenerative techniques in Periodontics, Implant Dentistry, Orthopedics or medical and dental surgery procedures that require bone neoformation. It can be used in the reconstruction of traumatic or degenerative bone wall defects, sinus floor elevation, periodontal or alveolar bone filling and osteotomies, as well as the site preservation and preparation. In medical procedures, it is used in orthopedics and traumatology cases such as correction of musculoskeletal tumors, spinal chord and cervical spine injuries.



Origin: 100% synthetic.
Phase Purity
≥ 95%.
Over 80%.
Gradually and completely resorbable.





The prices do not include VAT

37 EUR 16057 od 0,10 do 0,50 mm0,5 g - 1,9 cc
72 EUR 16062 od 0,10 do 0,50 mm3 g - 11,5 cc




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